Donor Screening

Our donors are recruited from local universities and colleges and are between the ages of 19 and 39. Most of them are undergraduate and graduate students; some are professionals. Due to our rigorous screening process, less than 3% of the applicants are eventually accepted as contributing donors.

Potential sperm donors possessing pleasant and acceptable physical features undergo extensive screening. This includes, but is not limited to, character and personality evaluation, genetic testing, fertility assessment, physical examination and infectious disease testing. Once accepted into the program, the health status of the donor is continually re-assessed.

Manhattan CryoBank takes the health of its donors and its recipients seriously. Before being approved as a donor, every potential donor is required to complete a comprehensive three-generation Medical History Questionnaire regarding the health of the donor and the donor’s blood relatives. Also included are questions for high-risk behaviors developed by the U.S. Centers for Disease Control and Prevention (CDC). Any affirmative answer to the CDC questions automatically disqualifies a potential donor. To assess sperm count and motility, a semen analysis and test freeze is done on two ejaculates before the donor is accepted.

Initial screening includes but is not limited to the following:

Semen samples from screened and accepted donors are quarantined for a minimum of 180 days and released only after re-testing of the donor for the required infectious disease screening and contingent upon the medical director’s approval. Donors are required to update the medical history questionnaires and to have a physical examination every six months.

The following tests are done at three or six-months intervals and are required by the FDA to release samples from quarantine:

*West Nile Virus is performed once every month between April and October for all active sperm donors.

Genetic Testing & Chromosome Analysis

Manhattan CryoBank believes in providing responsible genetic carrier screening tests regardless of ethnicity/nationality. Therefore, Manhattan CryoBank changed its genetic testing policy on November 1, 2014 to include more genetic tests to be performed on all donors using next-generation DNA sequencing methodology. Next-generation DNA sequencing methodology provides more comprehensive evaluations of genetic carrier status than traditional carrier screening methodologies.

Please note that the new genetic testing policy only applies to new donors accepted into the program on or after November 1, 2014. See each donor's short profile for completed genetic testing. 

Genetic Testing Policy for Donors Donating Prior to November 1, 2014:

Genetic Testing Policy for New Donors on/after November 1, 2014 (All Donors):

A Karyotype (Chromosome Analysis) is also performed on all donors that started donating after November 1, 2014.

Manhattan CryoBank offers additional genetic testing with GenePeeks, a breakthrough service that identifies disease risk for over 1,000+ conditions not included in the standard screening process.  The GenePeeks technology works by analyzing how a pair of genomes—a client's and a donor's—would work together.

You can view the 1,000+ conditions covered by the GenePeeks screen on their Conditions List. To order the service, please visit www.GenePeeks.com.